私達は環境保健の推進により 子どもたちのより良い未来を 実現させます。
私達は環境保健の推進により 子どもたちのより良い未来を 実現させます。

お知らせ

ラジオNIKKEI第1 小児科診療 UP-to-DATE

2022年8月30日

2022年8月16日火曜日 23:15～23:30放送のラジオNIKKEI第1 小児科診療 UP-to-DATEにおいて、「日本版乳幼児発達検査 J-ASQ®-3」が紹介されました。...

もっと見る
ジャンプする男の子と女の子

目的

当法人は、環境保健に関する正しい知識の普及を通じて国民の健康増進に寄与することを目的とし、その目的を達成するために次の事業を行います。

  • １環境保健に関わる研究者のネットワーク作り推進事業
  • ２環境保健に関わる研究助成事業
  • ３環境保健に関わる研修会の開催
  • ４環境保健に関わる講演会等への講師派遣事業
  • ５環境保健に関わる研究・相談・開発事業
  • ６出版事業
  • ７前各号に附帯する一切の事業

事務局

〒156-0051  東京都世田谷区宮坂1-27-6

一般社団法人環境保健推進協会

お問い合わせ
しろくまのイラスト

日本語版ASQ-3とは

ASQは、米国オレゴン大学によって開発された発達スクリーニングツールであり、その第3版であるASQ-3は、Squires J、Bricker Dらによって2009年に出版されています。月齢1か月から66か月の乳幼児の発達状況を、5領域（コミュニケーション、粗大運動、微細運動、問題解決、個人・社会）に関して、両親か主な養育者が記入して発達の遅れをスクリーニングすることができる発達評価ツールです。

日本語版ASQ-3（J-ASQ-3）は，環境省の実施する「子どもの健康と環境に関する全国調査（エコチル調査）」のパイロット調査（エコチル調査パイロット調査）に参加いただいた約400人のお子さんのデータより、0～5歳の10種類のJ-ASQ-3 質問紙の結果をまとめ、日本における基準値を設定しました。

また、その結果を用い、国立成育医療研究センターと東京・世田谷のクリニックに受診されたお子さんにご協力いただき、発達遅滞のお子さんをスクリーニングするために一定の信頼がおける質問紙であることを検証しました（詳細はこちら）。

最終的には、全国10 万人のお子さんとその親が参加しているエコチル調査の結果を検討し、より信頼性の高い基準に改善がなされる予定です。（研究目的の使用はこちら）

日本語版ASQ-3表紙
生活しているこどもたち
生活している子どもたち

日本語版ASQ-3が引用されている主な研究論文

原著

  • Mezawa H, Aoki S, Nakayama SF, et al. Psychometric profile of the Ages and Stages Questionnaires, Japanese translation. Pediatr Int. 2019;61(11):1086-1095. doi:10.1111/ped.13990.
  • 公開ウェブで確認できた主な被引用文献（2026年6月8日時点）

  • 2021

    Yasumitsu-Lovell K, et al.
    Birth month and infant gross motor development: results from the Japan Environment and Children’s Study.
    PLoS One. 2021.

    Sanefuji M, et al.
    Physical growth and neurodevelopment during the first year of life: a cohort study of the Japan Environment and Children’s Study.
    BMC Pediatrics. 2021.

    Sanefuji M, et al.
    Breast feeding and infant development in a cohort with sibling pair analysis: the Japan Environment and Children’s Study.
    2021.

    Minatoya M, et al.
    Association between early life child development and family dog ownership: a prospective birth cohort study of the Japan Environment and Children’s Study.
    2021.

    Nakahara K, et al.
    Association of maternal sleep before and during pregnancy with preterm birth and early infant outcomes.
    2021.

    Nakahara K, et al.
    Influence of physical activity before and during pregnancy on maternal and infant health: the Japan Environment and Children’s Study.
    2021.

    Matsumura K, et al.
    Prospective association of air-purifier usage during pregnancy with infant neurodevelopment: a nationwide longitudinal study – Japan Environment and Children’s Study.
    Journal of Clinical Medicine. 2020/2021.

    2022

    Kobayashi S, et al.
    Impact of prenatal exposure to mercury and selenium on child neurodevelopment.
    Environment International. 2022.

    Yamamoto M, et al.
    Longitudinal analyses of maternal and cord blood manganese levels and neurodevelopment in children up to 3 years of age: The Japan Environment and Children’s Study.
    Environment International. 2022.

    Muthusamy S, Wagh D, Tan J, Bulsara M, Rao S.
    Utility of the Ages and Stages Questionnaire to identify developmental delay in children aged 12 to 60 months: a systematic review and meta-analysis.
    JAMA Pediatrics. 2022;176(10):980–989. doi:10.1001/jamapediatrics.2022.3079.
    ※JAMA Pediatrics本文で、Mezawa et al. 2019の引用を確認。

    Motoki N, et al.
    Impact of maternal dyslipidemia on infant neurodevelopment.
    Brain and Development. 2022.
    ※本文参考文献で、Mezawa et al. 2019の引用を確認。

    Masumoto T, et al.
    Association between prenatal cadmium exposure and child development.
    2022.

    Miyake T, et al.
    Neurological development in 36-month-old children conceived via assisted reproductive technology: The Japan Environment and Children’s Study.
    Reproductive Medicine and Biology. 2022.

    Nakahara K, et al.
    Association of maternal hemoglobin levels during pregnancy with child development.
    Health Science Reports. 2022.

    Hirata K, et al.
    Long-term outcomes of children with neonatal transfer.
    European Journal of Pediatrics. 2022.

    2023

    Sasaki H, et al.
    Results from the Japan Environment and Children’s Study.
    2023.

    Takahashi I, et al.
    Screen time at age 1 year and communication and problem-solving developmental delay at 2 and 4 years.
    JAMA Pediatrics. 2023.

    Yamamoto M, et al.
    Screen time and developmental performance among children at 1–3 years of age in the Japan Environment and Children’s Study.
    JAMA Pediatrics. 2023.

    Nagata A, et al.
    Neurodevelopmental outcomes among offspring exposed to corticosteroid and β2-adrenergic agonists in utero.
    JAMA Network Open. 2023.

    Cibralic S, et al.
    Developmental screening tools for identification of children with developmental difficulties in high-income countries: a systematic review.
    Frontiers in Child and Adolescent Psychiatry. 2023.

    Noda M, et al.
    Association between combined spinal-epidural analgesia and child development.
    Journal of Obstetrics and Gynaecology Research. 2023.

    Aizawa M, et al.
    Association between frequency of breakfast intake before and during pregnancy and child development.
    Nutrition Journal. 2023.

    Maternal dietary fiber intake during pregnancy and child development: the Japan Environment and Children’s Study.
    2023.

    A nationwide, prospective cohort study on exogenous oxytocin and child development.
    2023.

    山本 緑.
    エコチル調査におけるデータベース研究.
    保健医療科学. 2023.

    2024

    Haneda K, et al.
    Gestational Age and Neurodevelopmental Delay in Term-born Children From the Japan Environment and Children’s Study.
    2024.

    Nagai T, et al.
    Association between general anesthesia in early childhood and neurodevelopment.
    Journal of Anesthesia. 2024.

    Inoue M, et al.
    Maternal dietary intake of fish and child neurodevelopment at 6 months and 1 year of age.
    Frontiers in Public Health. 2024.

    Hirai H, et al.
    Relationship between maternal consumption of fermented foods during pregnancy and child development: The Japan Environment and Children’s Study.
    PLoS One. 2024.

    Hirai H, et al.
    Relationship between frequency of yogurt consumption at 1 year of age and development at 3 years of age: The Japan Environment and Children’s Study.
    2024.

    Kikuchi K, et al.
    Infants’ early recovery from sleep disturbance is associated with developmental outcomes.
    Scientific Reports. 2024.

    Imanishi Y, et al.
    The association between maternal social support levels and child development at three years of age: the Japan Environment and Children’s Study.
    2024.

    Akagi T, et al.
    A prospective birth cohort study from the Japan Environment and Children’s Study.
    BMJ Open. 2024.
    ※BMJ Open本文の参考文献で、Mezawa et al. 2019の引用を確認。

    Sato K, et al.
    Absolute quantification of eight human milk components.
    Journal of Food Science. 2024.

    Kanamori K, et al.
    Group childcare has a positive impact on child development.
    Scientific Reports. 2024.
    ※PMC掲載本文の参考文献で、Mezawa et al. 2019の引用を確認。

    Tanaka T, et al.
    Maternal fermented food intake and infant neurodevelopment.
    2024.

    Nagata A, et al.
    Early childhood neurodevelopmental milestones in children with allergic diseases: the Japan Environment and Children’s Study.
    Scientific Reports. 2024.

    Yasumitsu-Lovell K, et al.
    Validity of the ESSENCE-Q neurodevelopmental screening tool.
    Developmental Medicine & Child Neurology. 2024.
    ※Wiley本文でMezawa et al. 2019の引用を確認。

    Early life exposure to indoor air pollutants and the risk of neurodevelopmental delays: The Japan Environment and Children’s Study.
    2024.

    2025

    Itoh M, et al.
    Impact of prenatal exposure to per- and polyfluoroalkyl substances on child neurodevelopment.
    Environment International. 2025.

    Mezawa H, et al.
    Associations between maternal exposure to per- and polyfluoroalkyl substances and child development outcomes.
    Environment International. 2025.
    ※PubMedでPFAS曝露と2歳・4歳時発達アウトカムを扱う論文として確認。

    Matsumura K, Tanaka T, Kuroda M, et al.
    Maternal Psychological Distress Before and After Childbirth and Neurodevelopmental Delay in Toddlers.
    JAMA Network Open. 2025.

    Hirokawa K, et al.
    Associations between parents’ broader autism phenotype and children’s developmental difficulty scores at 6 and 12 months: A prospective study.
    2025.
    ※SAGE Journals本文で日本語版ASQ-3およびMezawa et al. 2019の引用を確認。

    Child developmental patterns across subtypes of neurodevelopmental conditions.
    medRxiv. 2025.

    2026

    Nakamura H, Suzuki T, Kanamori K, Ota C, et al.
    Impact of Shared Storybook Reading on Child Development: The Japan Environment and Children’s Study.
    Pediatric Research. 2026.
    ※Nature掲載本文の参考文献で、Mezawa et al. 2019の引用を確認。

    Takaguchi K, et al.
    Sub-cohort study on the second phase of the Chiba Regional Centre of the Japan Environment and Children’s Study.
    BMJ Open. 2026.
    ※PMC掲載本文の参考文献で、Mezawa et al. 2019の引用を確認。

    Nishigori T, Nishigori H, Sato A, et al.
    Association between maternal bonding difficulty and neurodevelopmental delay in children aged 2 to 4 years: the Japan Environment and Children’s Study.
    Journal of Developmental Origins of Health and Disease. 2026.

    Nishigori H, Nishigori T, Obara T, et al.
    Paternal bonding failure and depression at 1 month postpartum are associated with neurodevelopmental delay in 4-year-old children: An Adjunct Study of the Japan Environment and Children’s Study.
    Infant Mental Health Journal. 2026.

    Kumasaka I, et al.
    Physical Activity Before and During Pregnancy and Neurodevelopment in Early Childhood.
    JAMA Network Open. 2026.

    Arai H, et al.
    Growth and Neurodevelopment to 18 Months in Infant With …
    Pediatrics International. 2026.

ネコと女の子